How can cyanide poisoning be treated

Basic life support includes immediate administration of high flow of oxygen, airway protection and cardiopulmonary resuscitation.

Advanced life support includes mechanical ventilation, catecholamine and sodium bicarbonate infusion. Supportive treatment is efficient but does not modify the time course or the body burden of cyanide.

Numerous antidotes are available. Oxygen counteracts efficiently cyanide action at the mitochondrial level. Sodium thiosulfate, methemoglobin forming agents and cobalt compounds act efficiently by complexing or transforming cyanide into non-toxic stable derivatives.

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Changes in the basal ganglia following cyanide poisoning. J Comput Assist Tomogr. J Neural Transm Suppl. J Bioenerg Biomembr. Free Radic Biol Med. Reaction of cyanide with oxidized and reduced enzyme. Biochim Biophys Acta. Baud FJ: Cyanide: critical issues in diagnosis and treatment. Hum Exp Toxicol.

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Early diagnosis and treatment are key to reducing your risk of complications. Moderate levels of acute or chronic exposure may also be resolved with quick diagnosis and treatment. In severe cases, symptoms are often sudden and life-threatening.

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Learn about gasoline poisoning, carbon monoxide poisoning, when to seek help, and…. How you can protect yourself, and what to do if you are exposed to cyanide Since breathing it is likely to be the primary route of exposure to cyanide, leave the area where the cyanide gas was released and get to fresh air. Quickly moving to an area where fresh air is available is highly effective in reducing exposure to cyanide gas.

If the cyanide gas was released outdoors, move away from the area where it was released. If you cannot get out of the area where the cyanide gas was released, stay as low to the ground as possible. If the release of cyanide gas was indoors, get out of the building. For more information on evacuation during a chemical emergency, see Facts About Evacuation. For more information on sheltering in place during a chemical emergency, see Facts About Sheltering in Place.

If you think you may have been exposed to cyanide, you should remove your clothing, rapidly wash your entire body with soap and water, and get medical care as quickly as possible. Removing your clothing: Quickly take off clothing that may have cyanide on it. Any clothing that has to be pulled over the head should be cut off the body instead of pulled over the head.

If you are helping other people remove their clothing, try to avoid touching any contaminated areas, and remove the clothing as quickly as possible. Washing yourself: As quickly as possible, wash any cyanide from your skin with large amounts of soap and water.

Washing with soap and water will help protect people from any chemicals on their bodies. If your eyes are burning or your vision is blurred, rinse your eyes with plain water for 10 to 15 minutes. If you wear contacts, remove them and put them with the contaminated clothing. Do not put the contacts back in your eyes even if they are not disposable contacts.

If you wear eyeglasses, wash them with soap and water. You can put your eyeglasses back on after you wash them. If you are wearing jewelry that you can wash with soap and water, you can wash it and put it back on.