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Please see our Privacy Policy for more information. The US Food and Drug Administration FDA on Wednesday finalized guidance on extending the expiration dates of the antibiotic doxycycline for state-level emergency response stockpiles.
FDA first issued a draft version of the guidance in April in response to requests from state emergency response stakeholders who were looking for ways to extend the shelf life of doxycycline beyond the labeled expiration date to treat inhalation anthrax or for post-exposure prophylaxis against anthrax. FDA says the final guidance has been updated to clarify some of the language present in the draft version, but does not feature any changes in policy from the earlier document.
Therefore, this would make it more obvious that the liquid or solution form of antibiotics has diminished in potency or efficacy and is therefore not safe to be used after expiry. Even some solid forms of antibiotics can have a narrow therapeutic index, and so a very minor decrease in pharmacological activity can result in serious consequences for patients. One such antibiotic is the monoclonal antibodies. Such medications should not be used beyond the expiry date.
The ability for antibiotics to retain their efficacy after they expire also depends on the conditions they are stored in. The best and most obvious way to store antibiotics is to follow any storage instructions provided in the packaging. This rule also applies when storing other medications. Any antibiotics should remain stable and retain their potency when stored in dry, cool spaces away from light or heat.
Avoid leaving your antibiotics in the car. It can be exposed to outside environmental conditions, such as cold and heat, and may reduce its potency. Sometimes such exposures can cause the antibiotics to go bad before the official expiry date. It is highly recommended that you do not store antibiotics in bathroom cabinets as it can be affected by heat and humidity. Even if the potency and efficacy of antibiotics may remain after expiration, do not take the expired antibiotics.
Even if there is no evidence of the antibiotics expiring or going bad, you should never take expired medicines. If for some reason it is an emergency and your antibiotics are past the expiration date, but there is no other evidence of the medicine going bad, then it may be acceptable. However, you should call your doctor for advice beforehand.
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